Tataniano was a surprise withdrawal from the Irish Independent Arkle Trophy at the confirmation stage.
The six-year-old, trained by Paul Nicholls, bypasses Tuesday's two-mile novice championship at Cheltenham in favour of the Johnny Henderson Grand Annual Handicap Chase on Friday.
"He's absolutely fine, but we just didn't think he was good enough for the Arkle and he's going to go for the Grand Annual instead," said owner Andy Stewart.
"It was obviously disappointing when he was beaten by a horse of Emma Lavelle's (Suntini) at Newbury last time and while he could be placed in an Arkle, he probably wouldn't be good enough to win it.
"Novices have a reasonably good record in the Grand Annual and he should have a good chance of winning that, so hopefully it works out. We obviously lined Poquelin up for the Grand Annual last year but that didn't work out, so hopefully Tataniano can do the business. I may still have a runner in the Arkle as I own Nomecheki."
Irish adversaries Captain Cee Bee and Sizing Europe are set for a deciding showdown after 17 horses stood their ground for the Arkle. When they clashed at Leopardstown on Boxing Day there was little between them at the final fence until Captain Cee Bee came down, leaving Sizing Europe to land the spoils.
Connections of both horses report their charges to be on song for the big day and trainer Henry de Bromhead said: "Everything is good with Sizing Europe and it is just a case of keeping him in one piece now. He's done plenty of work and we'll just keep him ticking over now until he heads over to Cheltenham on Saturday.
"We obviously had the trouble with transit fever last year but we have a few ideas of how to do things differently and try to prevent it happening again, so hopefully it was a one-off."
The Eddie Harty-trained Captain Cee Bee, successful in the Supreme Novices' Hurdle in 2008, returned to winning ways at Naas last month.
"Touch-wood, he's on course for the Arkle. He's in great form and fingers crossed he'll get there in one piece," said owner JP McManus's racing manager Frank Berry. "He goes there in good order and we hope for the best."